A c-Myc-MicroRNA functional feedback loop affects hepatocarcinogenesis
نویسندگان
چکیده
منابع مشابه
Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis
Deregulated activity of the c-Myc protooncogene is a frequent molecular event underlying mouse and human hepatocarcinogenesis. Nonetheless, the mechanisms sustaining c-Myc oncogenic activity in liver cancer remain scarcely delineated. Recently, we showed that the mammalian target of rapamycin complex 1 (mTORC1) cascade is induced and necessary for c-Myc dependent liver tumor development and pro...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2013
ISSN: 0270-9139
DOI: 10.1002/hep.26302